General Information

  • ID:  hor002536
  • Uniprot ID:  NA
  • Protein name:  Neokyotorphin
  • Gene name:  NA
  • Organism:  Spermophilus undulatus
  • Family:  NA
  • Source:  Animal
  • Expression:  brain
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  TSKYR
  • Length:  5
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Depressive effects on rhythmic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002536_AF2.pdbhor002536_ESM.pdb

Physical Information

Mass: 72525 Formula: C28H47N9O9
Absent amino acids: ACDEFGHILMNPQVW Common amino acids: KRSTY
pI: 10.45 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 0
Hydrophobicity: -224 Boman Index: -2658
Half-Life / Aliphatic Index: 7.2 hour Aliphatic Index: 0
Instability Index: -2582 Extinction Coefficient cystines: 1490
Absorbance 280nm: 372.5

Literature

  • PubMed ID:  10727797
  • Title:  State-dependent Effects of Some Neuropeptides and Neurotransmitters on Neuronal Activity of the Medial Septal Area in Brain Slices of the Ground Squirrel, Citellus Undulatus